分析与监测

固体三元稳态ClO2急性经口、遗传及蓄积毒性研究

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  • 南京理工大学化工学院, 江苏 南京 210094
李新杰(1966- ),环境科学与工程专业,硕士,在职博士生,南京理工大学化工学院水处理工程技术中心,工程师。电话:025-4316732。

收稿日期: 2001-11-08

  网络出版日期: 2010-10-01

Researches on the acute oral, heredity and cumulative toxicity of tr inary solid stable chlorine dioxide disinfectant

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  • Chemical Institute, Nanjing University of Science and Technology, Nanjing 210094, China

Received date: 2001-11-08

  Online published: 2010-10-01

摘要

固体三元稳态二氧化氯是为了解决二元产品活化率低、活化酸度高、活化损失大的缺点而研制出的新型固体ClO2产品。通过对其急性经口毒性、遗传毒性及蓄积毒性的试验研究,发现雌雄小鼠的急性经口LD50值均大于21.5g/kg,该产品属于实际无毒级;剂量达5.00g/kg,未检出对雌雄小鼠骨髓嗜多染红细胞的诱变活性;给药20d后,动物死亡仍未足半数,K>5,该产品为弱蓄积性。

本文引用格式

李新杰, 唐淑娟, 包训祥 . 固体三元稳态ClO2急性经口、遗传及蓄积毒性研究[J]. 工业水处理, 2002 , 22(4) : 45 -46 . DOI: 10.11894/1005-829x.2002.22(4).45

Abstract

Trinary solid stable chlorine dioxide is a newtype of disinfectant.I t is bet ter than the binary product s,overcoming the disadvantages such as having lowactivation rate,high activ ation acidity and great activation loss.Through experiments on its acute o ral,heredity and cumulative toxicity of ClO2,it is noticed that the acute oral LD50 of mice are more than 21.5 g/kg weight.So,this disinfectant is actually nontoxic.When the dosage is up to 5 g/kg weight no evocating activation of both male and female mice' s marrowpoly chromatic erythrocyte can be founded.After 20 day' s application of this disinfectant,the number of dead animal is still less than 50 %,the cumulative coef ficient K >5,so it is weak in cumulative property.

参考文献

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