Aiming at the feature of the wastewater from pharmaceuticals production of Zhejiang Shengda Co., Ltd., the wastewater is treated separately. The highly concentrated wastewater is oxidized by Fenton reagent before mixing with low concentrated wastewater which is followed by the use of hydrolytic acidation-contact oxidationair floatation-oxidation. The water quality of effluent after the treatment reaches the National Class-Ⅰ Standard of GB 8978—1996.