In order to solve the problem of lower refinery circulating cooling water concentration caused by some kinds of oil pollution, the high concentration treatment scheme to refine oil-bearing circulating cooling water has been selected through static scale inhibition experiment, and corrosion inhibition experiment in the conditions of containing oil and the experiment cooperated with bactericide. The medium dynamic simulated experiment and the application result show that the scheme has good corrosion and scale inhibition performance and has good efficiency to remove oil and bacteria.